Endocrine Abstracts

Congenital hypogonadotropic hypogonadism is a rare reproductive disorder characterised by isolated deficiency in the secretion or action of gonadotropin-releasing hormone (GnRH). Diminished GnRH activity in the immediate postnatal months, a period known as minipuberty, has severe consequences on the ontogenesis of male reproductive tract. Affected infant boys may present with micropenis and cryptorchidism. Rarely, adolescents with CHH present with delayed puberty in associatio...